Jia-Yin Ma has completed master degree of Chung Yuan Christian University. She specializes in cancer psychology,and also is a clinical psychologist of Taipei city hospital in Taiwan. She has published a research in conference of Taiwan Association of Clinical Psychology. Chun-Yu Huang has completed PhD from National Chengchi University. Now she is a clinical psychologist, and a professor of Chung Yuan Christian University. Chun-Yu Huang has studied many resarch of health pcychology, especially about psychology state of cancer survivor.
This study aims to consider the adaptation process of disease within breast cancer patients and their partners, including communication pattern, the perceived quality of the relationship and quality of life. This study is a cross-sectional design, and 257 breast cancer patients and their partners are participated. As analysis methods, we applied correlation analysis, difference analysis, multiple regression analysis and dyadic data analysis through the actor-partner interdependence model (APIM). The results revealed the points as followed: 1. Not only patients but their partner perceived themselves are demand-discussion, and others are withdraw-discussion, they have worse satisfactory quality of relationship.2. By using the APIM, the consequence revealed that the cancer-related communication pattern of each person is the strongest predictor of their own quality of relationship. The communication pattern of woman breast cancer patient’s perception also plays a significant role on their male partner’s quality of relationship. 3. Quality of relationship is a mediator variable between the cancer-related communication patterns and quality of life. For patients, quality of relationship is consistent with full mediated between the cancer-related communication patterns and all domain of quality of life. In conclusion, disease does have an impact on relationship. Besides, for cancer patients and their partners, we encourage partners to accompany patients for medical treatment, be patient’s primary caregiver, and provide more assistance to patients. Clinicians should be aware of the communication between the patients and their partners in order to help them to improve their communication skills and the quality of their relationship.
Yeni Purnamasari has completed her Master Degree of Biomedical Sicience at the age of 25 from Brawijaya University and now assigned as Internship Doctor in Aisyiyah Hospital Malang in East Java, Indonesia.
Coelomic fluid of the earthworm had a lot of bioactive substances as therapeutic drug and anticancer effect that has been proven in many medical research. The benefit of coelomic fluid as anticancer effect needs further investigation. This study aimed to investigate whether the coelomic fluid of the earthworm Lumbricus rubellus as combination of 5-Fluouracil has role in decreasing focal adhesion kinase (FAK) and calcium intracellular expression (iCa2-) on colorectal cancer HT-29 cell line. HT-29 cells were cultured by adding coelomic fluid with 5-Fluouracil (5,10, and 20 g/ml) and without 5-Fluouracil (0, 20 g/ml) for 24 hours. We assessed the percentage of FAK level using flowcytometri and iCa2+ using immune-fluorescence. The result showed that after treating HT-29 cells with combination of coelomic fluid and 5-Fluouracil in different concentration, the percentage FAK level significantly decreased in dose combination (p < 0.05) and iCa2+ percentage compare each groups was significantly differences (p< 0.05). Corelation between percentage FAK and iCa2+ showed that there is a strong correlation (R = 0.77). This suggest that treating combination coelomic fluid and 5-fluouracil in HT-29 cells made the decrease in FAK percentage and also followed by iCa2+ percentage. Our finding suggested that coelomic fluid of the earthworm Lumbricus rubellus could prove useful as a combination of 5-fluouracil in colorectal cancer therapy.